A cathepsin C-like protease mediates the post-translation modification of Toxoplasma gondii secretory proteins for optimal invasion and egress

Microbial pathogens use proteases for their infections, such as digestion of proteins for nutrients and activation of their virulence factors. As an obligate intracellular parasite, Toxoplasma gondii must invade host cells to establish its intracellular propagation. To facilitate invasion, the paras...

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Detalles Bibliográficos
Autores principales: Thornton, L. Brock, Key, Melanie, Micchelli, Chiara, Stasic, Andrew J., Kwain, Samuel, Floyd, Katherine, Moreno, Silvia N.J., Dominy, Brian N., Whitehead, Daniel C., Dou, Zhicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470614/
https://www.ncbi.nlm.nih.gov/pubmed/37326431
http://dx.doi.org/10.1128/mbio.00174-23

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