African swine fever virus MGF-360-10L is a novel and crucial virulence factor that mediates ubiquitination and degradation of JAK1 by recruiting the E3 ubiquitin ligase HERC5

African swine fever virus (ASFV) causes acute hemorrhagic infectious disease in pigs. The ASFV genome encodes various proteins that enable the virus to escape innate immunity; however, the underlying mechanisms are poorly understood. The present study found that ASFV MGF-360-10L significantly inhibi...

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Detalles Bibliográficos
Autores principales: Li, Dan, Peng, Jiangling, Wu, Junhuang, Yi, Jiamin, Wu, Panxue, Qi, Xiaolan, Ren, Jingjing, Peng, Gaochuang, Duan, Xianghan, Ru, Yi, Liu, Huanan, Tian, Hong, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470787/
https://www.ncbi.nlm.nih.gov/pubmed/37417777
http://dx.doi.org/10.1128/mbio.00606-23

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