Global analysis of putative phospholipases in Plasmodium falciparum reveals an essential role of the phosphoinositide-specific phospholipase C in parasite maturation

For its replication within red blood cells, the malaria parasite depends on a highly active and regulated lipid metabolism. Enzymes involved in lipid metabolic processes such as phospholipases are, therefore, potential drug targets. Here, using reverse genetics approaches, we show that only 1 out of...

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Detalles Bibliográficos
Autores principales: Burda, Paul-Christian, Ramaprasad, Abhinay, Bielfeld, Sabrina, Pietsch, Emma, Woitalla, Anna, Söhnchen, Christoph, Singh, Mehar Nihal, Strauss, Jan, Sait, Aaron, Collinson, Lucy M., Schwudke, Dominik, Blackman, Michael J., Gilberger, Tim-Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470789/
https://www.ncbi.nlm.nih.gov/pubmed/37489900
http://dx.doi.org/10.1128/mbio.01413-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470789/
https://www.ncbi.nlm.nih.gov/pubmed/37489900
http://dx.doi.org/10.1128/mbio.01413-23

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