Probing the drivers of Staphylococcus aureus biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases

Phenol-soluble modulins (PSMs) are the primary proteinaceous component of Staphylococcus aureus biofilms. Residence in the protective environment of biofilms allows bacteria to rapidly evolve and acquire antimicrobial resistance, which can lead to persistent infections such as those caused by methic...

Descripción completa

Detalles Bibliográficos
Autores principales: Howard, Matthew K., Miller, Karlie R., Sohn, Brian S., Ryan, Jeremy J., Xu, Andy, Jackrel, Meredith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470818/
https://www.ncbi.nlm.nih.gov/pubmed/37195208
http://dx.doi.org/10.1128/mbio.00587-23

Ejemplares similares

Ejemplares similares