Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV

Persons living with HIV (PLWH) have an increased risk for tuberculosis (TB). After prolonged and repeated exposure, some PLWH never develop TB and show no evidence of immune sensitization to Mycobacterium tuberculosis (Mtb) as defined by persistently negative tuberculin skin tests (TST) and interfer...

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Detalles Bibliográficos
Autores principales: Kroon, Elouise E., Correa-Macedo, Wilian, Evans, Rachel, Seeger, Allison, Engelbrecht, Lize, Kriel, Jurgen A., Loos, Ben, Okugbeni, Naomi, Orlova, Marianna, Cassart, Pauline, Kinnear, Craig J., Tromp, Gerard C., Möller, Marlo, Wilkinson, Robert J., Coussens, Anna K., Schurr, Erwin, Hoal, Eileen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470897/
https://www.ncbi.nlm.nih.gov/pubmed/37616312
http://dx.doi.org/10.1371/journal.pgen.1010888

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