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Backup transcription factor binding sites protect human genes from mutations in the promoter
This study was designed to test the idea that the regulatory regions of human genes have evolved to be resistant to the effects of mutations in their primary function, the control of gene expression. It is proposed that the transcription factor/transcription factor binding site (TF/TFBS) pair having...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10470901/ https://www.ncbi.nlm.nih.gov/pubmed/37651425 http://dx.doi.org/10.1371/journal.pone.0281569 |