Cargando…

Polygenic risk scores: the future of cancer risk prediction, screening, and precision prevention

Genome-wide association studies (GWASs) have shown that the genetic architecture of cancers are highly polygenic and enabled researchers to identify genetic risk loci for cancers. The genetic variants associated with a cancer can be combined into a polygenic risk score (PRS), which captures part of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yuzhuo, Zhu, Meng, Ma, Hongxia, Shen, Hongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471106/ https://www.ncbi.nlm.nih.gov/pubmed/37724297 http://dx.doi.org/10.1515/mr-2021-0025

Ejemplares similares

Polygenic score: An anchor holding the whole life course
por: Jin, Guangfu, et al.
Publicado: (2023)

Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
por: Hingorani, Aroon D, et al.
Publicado: (2023)

Statistical genetics and polygenic risk score for precision medicine
por: Konuma, Takahiro, et al.
Publicado: (2021)

Evaluation of polygenic risk score for risk prediction of gastric cancer
por: Wang, Xiao-Yu, et al.
Publicado: (2023)

Polygenic risk scores and breast cancer risk prediction
por: Roberts, Eleanor, et al.
Publicado: (2023)

The limits of personalization in precision medicine: Polygenic risk scores and racial categorization in a precision breast cancer screening trial
por: James, Jennifer Elyse, et al.
Publicado: (2021)

Polygenic Risk Scores for cancer mortality prediction
por: Sciurti, A, et al.
Publicado: (2023)

Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort
por: Lu, Hongxiang, et al.
Publicado: (2020)

Polygenic risk scores to stratify cancer screening should predict mortality not incidence
por: Vickers, Andrew J., et al.
Publicado: (2022)

Polygenic Risk Score Prediction for Endometriosis
por: Kloeve-Mogensen, Kirstine, et al.
Publicado: (2021)

Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions
por: Fatumo, Segun, et al.
Publicado: (2023)

Prediction of gastric cancer risk by a polygenic risk score of Helicobacter pylori
por: Wang, Xiao-Yu, et al.
Publicado: (2022)

Polygenic risk scores for prediction of breast cancer risk in Asian populations
por: Ho, Weang-Kee, et al.
Publicado: (2022)

Prostate cancer risk prediction using a polygenic risk score
por: Sipeky, Csilla, et al.
Publicado: (2020)

Power and Predictive Accuracy of Polygenic Risk Scores
por: Dudbridge, Frank
Publicado: (2013)

Polygenic risk scores: a biased prediction?
por: De La Vega, Francisco M., et al.
Publicado: (2018)

Polygenic risk scores for prediction of atrial fibrillation
por: Kavousi, Maryam, et al.
Publicado: (2022)

Implications of Lifestyle Factors and Polygenic Risk Score for Absolute Risk Prediction of Colorectal Neoplasm and Risk-Adapted Screening
por: Chen, Hongda, et al.
Publicado: (2021)

On cross-ancestry cancer polygenic risk scores
por: Fritsche, Lars G., et al.
Publicado: (2021)

Polygenic Risk Score, Lifestyles, and Type 2 Diabetes Risk: A Prospective Chinese Cohort Study
por: Liu, Jia, et al.
Publicado: (2023)

Evaluating the Potential of Polygenic Risk Score to Improve Colorectal Cancer Screening
por: Arnau-Collell, Coral, et al.
Publicado: (2022)

A Polygenic Risk Score to Predict Future Adult Short Stature Among Children
por: Lu, Tianyuan, et al.
Publicado: (2021)

A polygenic risk score for multiple myeloma risk prediction
por: Canzian, Federico, et al.
Publicado: (2021)

Testing the application of polygenic risk scores in the transplant setting – Relevance for precision medicine
por: Shaked, Abraham, et al.
Publicado: (2022)

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
por: Mavaddat, Nasim, et al.
Publicado: (2019)

Prostate cancer polygenic risk score and prediction of lethal prostate cancer
por: Klein, Robert J., et al.
Publicado: (2022)

A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening
por: He, Yong-Qiao, et al.
Publicado: (2022)

Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study
por: Forgetta, Vincenzo, et al.
Publicado: (2020)

Correction: Power and Predictive Accuracy of Polygenic Risk Scores
por: Dudbridge, Frank
Publicado: (2013)

Polygenic risk and hazard scores for Alzheimer's disease prediction
por: Leonenko, Ganna, et al.
Publicado: (2019)

Polygenic Risk Scores in Alzheimer's Disease: Current Applications and Future Directions
por: Baker, Emily, et al.
Publicado: (2020)

Evaluation of Polygenic Risk Scores for Prediction of Prostate Cancer in Korean Men
por: Oh, Jong Jin, et al.
Publicado: (2020)

Gastric Cancer Risk Prediction Using an Epidemiological Risk Assessment Model and Polygenic Risk Score
por: Park, Boyoung, et al.
Publicado: (2021)

Polygenic risk score opportunities for early detection and prevention strategies in endometrial cancer
por: O’Mara, Tracy A., et al.
Publicado: (2020)

Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries
por: Liang, Yanyu, et al.
Publicado: (2022)

Development and Validation of a Clinical Polygenic Risk Score to Predict Breast Cancer Risk
por: Hughes, Elisha, et al.
Publicado: (2020)

Incorporating Alternative Polygenic Risk Scores into the BOADICEA Breast Cancer Risk Prediction Model
por: Mavaddat, Nasim, et al.
Publicado: (2023)

Physical activity, polygenic risk score, and colorectal cancer risk
por: Chen, Xuechen, et al.
Publicado: (2022)

Polygenic risk score is a predictor of adenomatous polyps at screening colonoscopy
por: Northcutt, Michael J., et al.
Publicado: (2021)

Role of Polygenic Risk Score in Cancer Precision Medicine of Non-European Populations: A Systematic Review
por: Junior, Howard Lopes Ribeiro, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2d20kvo7dne8d2n232has7gnqg