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Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition
The liver has a high demand for phosphatidylcholine (PC), particularly in overnutrition, where reduced phospholipid levels have been implicated in the development of nonalcoholic fatty liver disease (NAFLD). Whether other pathways exist in addition to de novo PC synthesis that contribute to hepatic...
Autores principales: | Chin, Cheen Fei, Galam, Dwight L.A., Gao, Liang, Tan, Bryan C., Wong, Bernice H., Chua, Geok-Lin, Loke, Randy Y.J., Lim, Yen Ching, Wenk, Markus R., Lim, Miao-Shan, Leow, Wei-Qiang, Goh, George B.B., Torta, Federico, Silver, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471173/ https://www.ncbi.nlm.nih.gov/pubmed/37463052 http://dx.doi.org/10.1172/JCI171267 |
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