Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition

The liver has a high demand for phosphatidylcholine (PC), particularly in overnutrition, where reduced phospholipid levels have been implicated in the development of nonalcoholic fatty liver disease (NAFLD). Whether other pathways exist in addition to de novo PC synthesis that contribute to hepatic...

Descripción completa

Detalles Bibliográficos
Autores principales: Chin, Cheen Fei, Galam, Dwight L.A., Gao, Liang, Tan, Bryan C., Wong, Bernice H., Chua, Geok-Lin, Loke, Randy Y.J., Lim, Yen Ching, Wenk, Markus R., Lim, Miao-Shan, Leow, Wei-Qiang, Goh, George B.B., Torta, Federico, Silver, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471173/
https://www.ncbi.nlm.nih.gov/pubmed/37463052
http://dx.doi.org/10.1172/JCI171267

Ejemplares similares

Ejemplares similares