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Reward prediction error in learning-related behaviors

Learning is a complex process, during which our opinions and decisions are easily changed due to unexpected information. But the neural mechanism underlying revision and correction during the learning process remains unclear. For decades, prediction error has been regarded as the core of changes to...

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Detalles Bibliográficos
Autores principales: Deng, Yujun, Song, Da, Ni, Junjun, Qing, Hong, Quan, Zhenzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471312/
https://www.ncbi.nlm.nih.gov/pubmed/37662112
http://dx.doi.org/10.3389/fnins.2023.1171612
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author Deng, Yujun
Song, Da
Ni, Junjun
Qing, Hong
Quan, Zhenzhen
author_facet Deng, Yujun
Song, Da
Ni, Junjun
Qing, Hong
Quan, Zhenzhen
author_sort Deng, Yujun
collection PubMed
description Learning is a complex process, during which our opinions and decisions are easily changed due to unexpected information. But the neural mechanism underlying revision and correction during the learning process remains unclear. For decades, prediction error has been regarded as the core of changes to perception in learning, even driving the learning progress. In this article, we reviewed the concept of reward prediction error, and the encoding mechanism of dopaminergic neurons and the related neural circuities. We also discussed the relationship between reward prediction error and learning-related behaviors, including reversal learning. We then demonstrated the evidence of reward prediction error signals in several neurological diseases, including Parkinson’s disease and addiction. These observations may help to better understand the regulatory mechanism of reward prediction error in learning-related behaviors.
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spelling pubmed-104713122023-09-01 Reward prediction error in learning-related behaviors Deng, Yujun Song, Da Ni, Junjun Qing, Hong Quan, Zhenzhen Front Neurosci Neuroscience Learning is a complex process, during which our opinions and decisions are easily changed due to unexpected information. But the neural mechanism underlying revision and correction during the learning process remains unclear. For decades, prediction error has been regarded as the core of changes to perception in learning, even driving the learning progress. In this article, we reviewed the concept of reward prediction error, and the encoding mechanism of dopaminergic neurons and the related neural circuities. We also discussed the relationship between reward prediction error and learning-related behaviors, including reversal learning. We then demonstrated the evidence of reward prediction error signals in several neurological diseases, including Parkinson’s disease and addiction. These observations may help to better understand the regulatory mechanism of reward prediction error in learning-related behaviors. Frontiers Media S.A. 2023-08-17 /pmc/articles/PMC10471312/ /pubmed/37662112 http://dx.doi.org/10.3389/fnins.2023.1171612 Text en Copyright © 2023 Deng, Song, Ni, Qing and Quan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Deng, Yujun
Song, Da
Ni, Junjun
Qing, Hong
Quan, Zhenzhen
Reward prediction error in learning-related behaviors
title Reward prediction error in learning-related behaviors
title_full Reward prediction error in learning-related behaviors
title_fullStr Reward prediction error in learning-related behaviors
title_full_unstemmed Reward prediction error in learning-related behaviors
title_short Reward prediction error in learning-related behaviors
title_sort reward prediction error in learning-related behaviors
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471312/
https://www.ncbi.nlm.nih.gov/pubmed/37662112
http://dx.doi.org/10.3389/fnins.2023.1171612
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