Elevated interleukin-10 levels in patients with ocular toxoplasmosis

In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are hel...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Gee-Hyun, Kwak, Jae Hyuck, Park, Young-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Parasitology and Tropical Medicine 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471474/
https://www.ncbi.nlm.nih.gov/pubmed/37648237
http://dx.doi.org/10.3347/PHD.22172
_version_ 1785099857307893760
author Kim, Gee-Hyun
Kwak, Jae Hyuck
Park, Young-Hoon
author_facet Kim, Gee-Hyun
Kwak, Jae Hyuck
Park, Young-Hoon
author_sort Kim, Gee-Hyun
collection PubMed
description In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.
format Online
Article
Text
id pubmed-10471474
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher The Korean Society for Parasitology and Tropical Medicine
record_format MEDLINE/PubMed
spelling pubmed-104714742023-09-01 Elevated interleukin-10 levels in patients with ocular toxoplasmosis Kim, Gee-Hyun Kwak, Jae Hyuck Park, Young-Hoon Parasites Hosts Dis Brief Communication In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor. The Korean Society for Parasitology and Tropical Medicine 2023-08 2023-08-21 /pmc/articles/PMC10471474/ /pubmed/37648237 http://dx.doi.org/10.3347/PHD.22172 Text en © 2023 The Korean Society for Parasitology and Tropical Medicine https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Communication
Kim, Gee-Hyun
Kwak, Jae Hyuck
Park, Young-Hoon
Elevated interleukin-10 levels in patients with ocular toxoplasmosis
title Elevated interleukin-10 levels in patients with ocular toxoplasmosis
title_full Elevated interleukin-10 levels in patients with ocular toxoplasmosis
title_fullStr Elevated interleukin-10 levels in patients with ocular toxoplasmosis
title_full_unstemmed Elevated interleukin-10 levels in patients with ocular toxoplasmosis
title_short Elevated interleukin-10 levels in patients with ocular toxoplasmosis
title_sort elevated interleukin-10 levels in patients with ocular toxoplasmosis
topic Brief Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471474/
https://www.ncbi.nlm.nih.gov/pubmed/37648237
http://dx.doi.org/10.3347/PHD.22172
work_keys_str_mv AT kimgeehyun elevatedinterleukin10levelsinpatientswithoculartoxoplasmosis
AT kwakjaehyuck elevatedinterleukin10levelsinpatientswithoculartoxoplasmosis
AT parkyounghoon elevatedinterleukin10levelsinpatientswithoculartoxoplasmosis

Ejemplares similares