Catalyst- and metal-free C(sp(2))–H bond selenylation of (N-hetero)-arenes using diselenides and trichloroisocyanuric acid at room temperature

In this paper, we report an eco-friendly approach for the C(sp(2))–H bond selenylation of imidazopyridines and other N-heteroarenes as well as simple arenes at ambient temperature. This new protocol consists of the reaction between (N-hetero)-arenes and the diorganyl-diselenides and trichloroisocyan...

Descripción completa

Detalles Bibliográficos
Autores principales: Neto, José S. S., Granja, Isis J. A., Scheide, Marcos R., Franco, Marcelo S., Moraes, Cassio A. O., Beatriz, Adilson, de Lima, Dênis P., Botteselle, Giancarlo V., Frizon, Tiago E. A., Saba, Sumbal, Rafique, Jamal, Braga, Antonio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471583/
https://www.ncbi.nlm.nih.gov/pubmed/37652946
http://dx.doi.org/10.1038/s41598-023-41430-9
Descripción
Sumario:In this paper, we report an eco-friendly approach for the C(sp(2))–H bond selenylation of imidazopyridines and other N-heteroarenes as well as simple arenes at ambient temperature. This new protocol consists of the reaction between (N-hetero)-arenes and the diorganyl-diselenides and trichloroisocyanuric acid (TCCA)-ethanol reagent system. In a short reaction time, the desired selenylated products were obtained regioselectively in good yields, with tolerance for a wide range of functional groups.

Ejemplares similares