Cargando…

Genome-wide study of longitudinal brain imaging measures of multiple sclerosis progression across six clinical trials

While the genetics of MS risk susceptibility are well-described, and recent progress has been made on the genetics of disease severity, the genetics of disease progression remain elusive. We therefore investigated the genetic determinants of MS progression on longitudinal brain MRI: change in brain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Loomis, Stephanie J., Sadhu, Nilanjana, Fisher, Elizabeth, Gafson, Arie R., Huang, Yunfeng, Yang, Chengran, Hughes, Emily E., Marshall, Eric, Herman, Ann, John, Sally, Runz, Heiko, Jia, Xiaoming, Bhangale, Tushar, Bronson, Paola G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471679/ https://www.ncbi.nlm.nih.gov/pubmed/37652990 http://dx.doi.org/10.1038/s41598-023-41099-0

Ejemplares similares

Lesion-level correspondence and longitudinal properties of paramagnetic rim and slowly expanding lesions in multiple sclerosis
por: Elliott, Colm, et al.
Publicado: (2023)

Remote Monitoring in the Home Validates Clinical Gait Measures for Multiple Sclerosis
por: Supratak, Akara, et al.
Publicado: (2018)

Inflammatory Activity on Natalizumab Predicts Short-Term but Not Long-Term Disability in Multiple Sclerosis
por: Raffel, Joel, et al.
Publicado: (2017)

Serum Neurofilament Light and Multiple Sclerosis Progression Independent of Acute Inflammation
por: Gafson, Arie R., et al.
Publicado: (2022)

Glial fibrillary acidic protein and multiple sclerosis progression independent of acute inflammation
por: Jiang, Xiaotong, et al.
Publicado: (2023)

A randomized study of natalizumab dosing regimens for relapsing–remitting multiple sclerosis
por: Trojano, Maria, et al.
Publicado: (2021)

Lipoprotein markers associated with disability from multiple sclerosis
por: Gafson, A. R., et al.
Publicado: (2018)

Association of Serum Neurofilament Light Levels With Long-term Brain Atrophy in Patients With a First Multiple Sclerosis Episode
por: Plavina, Tatiana, et al.
Publicado: (2020)

Abnormalities in normal-appearing white matter from which multiple sclerosis lesions arise
por: Elliott, Colm, et al.
Publicado: (2021)

geneAttribution: trait agnostic identification of candidate genes associated with noncoding variation
por: Wuster, Arthur, et al.
Publicado: (2017)

Chronic lesion activity and disability progression in secondary progressive multiple sclerosis
por: Beynon, Vanessa, et al.
Publicado: (2022)

Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy
por: Khan, Zia, et al.
Publicado: (2023)

Safety, Patient-Reported Well-Being, and Physician-Reported Assessment of Walking Ability in Patients with Multiple Sclerosis for Prolonged-Release Fampridine Treatment in Routine Clinical Practice: Results of the LIBERATE Study
por: Castelnovo, Giovanni, et al.
Publicado: (2021)

RNAi–Based Functional Profiling of Loci from Blood Lipid Genome-Wide Association Studies Identifies Genes with Cholesterol-Regulatory Function
por: Blattmann, Peter, et al.
Publicado: (2013)

A deaf mother and son with diabetes and renal failure
por: Schanz, Jurik, et al.
Publicado: (2012)

Slowly expanding lesions are a marker of progressive MS – No
por: Arnold, Douglas L, et al.
Publicado: (2021)

Automated content analysis across six languages
por: Windsor, Leah Cathryn, et al.
Publicado: (2019)

Longitudinal assessment of anxiety and depression symptoms in U.S. adolescents across six months of the coronavirus pandemic
por: Bowen, Anne E., et al.
Publicado: (2022)

The burden of rare protein-truncating genetic variants on human lifespan
por: Liu, Jimmy Z., et al.
Publicado: (2022)

In vitro studies of adhesion properties of six lactic acid bacteria isolated from the longevous population of China
por: Guan, Chengran, et al.
Publicado: (2020)

Candidate gene association study suggests potential role of dopamine beta-hydroxylase in pain heterogeneity in sickle cell disease
por: Sadhu, Nilanjana, et al.
Publicado: (2023)

World right side up: investing across six continents
por: Mayer, Christopher W
Publicado: (2012)

Shared heritability and functional enrichment across six solid cancers
por: Jiang, Xia, et al.
Publicado: (2019)

Mononuclear cell transcriptome changes associated with dimethyl fumarate in MS
por: Gafson, Arie R., et al.
Publicado: (2018)

Evaluation of the effect of ambrisentan on digital microvascular flow in patients with systemic sclerosis using laser Doppler perfusion imaging: a 12-week randomized double-blind placebo controlled trial
por: Bose, Nilanjana, et al.
Publicado: (2015)

Large-scale longitudinal gradients of genetic diversity: a meta-analysis across six phyla in the Mediterranean basin
por: Conord, Cyrille, et al.
Publicado: (2012)

Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake
por: Zimoń, Magdalena, et al.
Publicado: (2021)

Determinants of Six-Minute Walk Test Performance in Women with Systemic Sclerosis
por: Sezgin, Nazenin Hande, et al.
Publicado: (2023)

Identify QTLs for grain size and weight in common wild rice using chromosome segment substitution lines across six environments
por: Qi, Lan, et al.
Publicado: (2017)

Sexual Debut Ages in Heterosexual Norwegians Across Six Birth Cohorts
por: Fischer, Nantje, et al.
Publicado: (2022)

Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders
por: Hettwer, M. D., et al.
Publicado: (2022)

Identifying and mitigating batch effects in whole genome sequencing data
por: Tom, Jennifer A., et al.
Publicado: (2017)

Rare genetic variants impact muscle strength
por: Huang, Yunfeng, et al.
Publicado: (2023)

Torus partition function of the six-vertex model from algebraic geometry
por: Lykke Jacobsen, Jesper, et al.
Publicado: (2018)

Spatial risk for a superspreading environment: Insights from six urban facilities in six global cities across four continents
por: Loo, Becky P. Y., et al.
Publicado: (2023)

S100B single nucleotide polymorphisms exhibit sex-specific associations with chronic pain in sickle cell disease in a largely African-American cohort
por: Jhun, Ellie H., et al.
Publicado: (2020)

Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe
por: Demircan, Kamil, et al.
Publicado: (2022)

Prevalence of cardiovascular risk factors across six African Immigrant Groups in Minnesota
por: Sewali, Barrett, et al.
Publicado: (2015)

Development and validation of the neighborhood environment walkability scale for youth across six continents
por: Cerin, Ester, et al.
Publicado: (2019)

Publisher Correction: Shared heritability and functional enrichment across six solid cancers
por: Jiang, Xia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1jr1jj9h136cd6h270g10qkb5t