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Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study
Despite Helicobacter pylori infection remains asymptomatic in most people, it is associated with an increased risk of gastric cancer. Considering Egypt had the highest prevalence of H. pylori in healthy asymptomatic population in adults and pediatric age in past studies and currently salivary ELISA...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471685/ https://www.ncbi.nlm.nih.gov/pubmed/37653065 http://dx.doi.org/10.1038/s41598-023-41246-7 |
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author | Mikhail, Christine Raouf George Abd El Maksoud Mohamed, Abeer Shaker, Olfat Gamil EL Desouky, Eman Shalaby, Rania Hassan |
author_facet | Mikhail, Christine Raouf George Abd El Maksoud Mohamed, Abeer Shaker, Olfat Gamil EL Desouky, Eman Shalaby, Rania Hassan |
author_sort | Mikhail, Christine Raouf George |
collection | PubMed |
description | Despite Helicobacter pylori infection remains asymptomatic in most people, it is associated with an increased risk of gastric cancer. Considering Egypt had the highest prevalence of H. pylori in healthy asymptomatic population in adults and pediatric age in past studies and currently salivary ELISA could be used for diagnosis of Oral H. pylori infection. Moreover, some researchers speculated that dentists and dental students might be at a higher risk for oral H. pylori infection because they are the most frequently exposed ones to saliva and dental plaque. This study aimed to determine risk factors associated with frequency of H. pylori among a sample of dental students for better management of the disease. 83 participants, with age (21–25 years), attending Faculty of Dentistry, Fayoum University were recruited. A structured questionnaire was used to collect information on sociodemographic parameters and risk factors for H. pylori. Direct inquiry about dyspeptic symptoms were done. Saliva samples were collected and tested for H. pylori antibodies. Overall seroprevalence was 22.9%. Participants in internship were more prone to be positive (p = 0.005). 32.6% of urban residents versus 10.8% of rural were H. pylori positive (p = 0.019). 75.0% of previous history of H. pylori infection versus 14.1% of those with no history were H. pylori positive p < 0.001. 70% of positive H. pylori participants reported positive clinical symptoms that were statistically significant. This study suggests that middle income, previous history of H. pylori and clinical symptoms of dyspepsia are risk factors of oral H. pylori with a decline in its prevalence in Egypt. |
format | Online Article Text |
id | pubmed-10471685 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-104716852023-09-02 Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study Mikhail, Christine Raouf George Abd El Maksoud Mohamed, Abeer Shaker, Olfat Gamil EL Desouky, Eman Shalaby, Rania Hassan Sci Rep Article Despite Helicobacter pylori infection remains asymptomatic in most people, it is associated with an increased risk of gastric cancer. Considering Egypt had the highest prevalence of H. pylori in healthy asymptomatic population in adults and pediatric age in past studies and currently salivary ELISA could be used for diagnosis of Oral H. pylori infection. Moreover, some researchers speculated that dentists and dental students might be at a higher risk for oral H. pylori infection because they are the most frequently exposed ones to saliva and dental plaque. This study aimed to determine risk factors associated with frequency of H. pylori among a sample of dental students for better management of the disease. 83 participants, with age (21–25 years), attending Faculty of Dentistry, Fayoum University were recruited. A structured questionnaire was used to collect information on sociodemographic parameters and risk factors for H. pylori. Direct inquiry about dyspeptic symptoms were done. Saliva samples were collected and tested for H. pylori antibodies. Overall seroprevalence was 22.9%. Participants in internship were more prone to be positive (p = 0.005). 32.6% of urban residents versus 10.8% of rural were H. pylori positive (p = 0.019). 75.0% of previous history of H. pylori infection versus 14.1% of those with no history were H. pylori positive p < 0.001. 70% of positive H. pylori participants reported positive clinical symptoms that were statistically significant. This study suggests that middle income, previous history of H. pylori and clinical symptoms of dyspepsia are risk factors of oral H. pylori with a decline in its prevalence in Egypt. Nature Publishing Group UK 2023-08-31 /pmc/articles/PMC10471685/ /pubmed/37653065 http://dx.doi.org/10.1038/s41598-023-41246-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Mikhail, Christine Raouf George Abd El Maksoud Mohamed, Abeer Shaker, Olfat Gamil EL Desouky, Eman Shalaby, Rania Hassan Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study |
title | Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study |
title_full | Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study |
title_fullStr | Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study |
title_full_unstemmed | Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study |
title_short | Frequency and risk factors of H. pylori infection among dental students: an observational cross-sectional study |
title_sort | frequency and risk factors of h. pylori infection among dental students: an observational cross-sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471685/ https://www.ncbi.nlm.nih.gov/pubmed/37653065 http://dx.doi.org/10.1038/s41598-023-41246-7 |
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