Interlukin-4 weakens resistance to stress injury and megakaryocytic differentiation of hematopoietic stem cells by inhibiting Psmd13 expression

Thrombocytopenia is a major and fatal complication in patients with acute myeloid leukemia (AML), which results from disrupted megakaryopoiesis by leukemic niche and blasts. Our previous research revealed that elevated interleukin-4 (IL-4) in AML bone marrow had adverse impact on multiple stages thr...

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Detalles Bibliográficos
Autores principales: Gao, Ai, Xu, Shuhui, Li, Qing, Zhu, Caiying, Wang, Fengjiao, Wang, Yajie, Hao, Sha, Dong, Fang, Cheng, Hui, Cheng, Tao, Gong, Yuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471741/
https://www.ncbi.nlm.nih.gov/pubmed/37653079
http://dx.doi.org/10.1038/s41598-023-41479-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471741/
https://www.ncbi.nlm.nih.gov/pubmed/37653079
http://dx.doi.org/10.1038/s41598-023-41479-6

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