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A primary Ewing’s sarcoma of the kidney: A case report and review of literature
Primary Ewing’s kidney sarcoma is a rare and aggressive cancer with poor treatment outcomes. Furthermore, clinical presentations are nonspecific, such as abdominal pain, abdominal mass, cachexia, or hematuria. Currently, there is no consensus guideline for the treatment of this condition. We report...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Wolters Kluwer - Medknow
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471821/ https://www.ncbi.nlm.nih.gov/pubmed/37664090 http://dx.doi.org/10.4103/ua.ua_2_23 |
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author | Senkhum, Ornsinee Attawettayanon, Worapat Pripatnanont, Choosak Chalieopanyarwong, Virote |
author_facet | Senkhum, Ornsinee Attawettayanon, Worapat Pripatnanont, Choosak Chalieopanyarwong, Virote |
author_sort | Senkhum, Ornsinee |
collection | PubMed |
description | Primary Ewing’s kidney sarcoma is a rare and aggressive cancer with poor treatment outcomes. Furthermore, clinical presentations are nonspecific, such as abdominal pain, abdominal mass, cachexia, or hematuria. Currently, there is no consensus guideline for the treatment of this condition. We report on a 22-year-old man who presented with gross hematuria for 3 weeks. Computed tomography demonstrated a huge right renal mass with a thrombus in the inferior vena cava (IVC) without visceral metastasis. A percutaneous tissue biopsy revealed Ewing’s sarcoma (ES) and the patient received neoadjuvant chemotherapy (doxorubicin and ifosfamide) for four cycles. This reduced the tumor’s size significantly and made it eligible for surgical intervention. Radical nephrectomy and tumor thrombus removal with wedge IVC wall were performed. The final diagnosis of ES was confirmed by the immunohistochemistry of the kidney specimen. After a 5-year follow-up of the patient, clinical and imaging evidence demonstrated that there was no disease recurrence. |
format | Online Article Text |
id | pubmed-10471821 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-104718212023-09-02 A primary Ewing’s sarcoma of the kidney: A case report and review of literature Senkhum, Ornsinee Attawettayanon, Worapat Pripatnanont, Choosak Chalieopanyarwong, Virote Urol Ann Case Report Primary Ewing’s kidney sarcoma is a rare and aggressive cancer with poor treatment outcomes. Furthermore, clinical presentations are nonspecific, such as abdominal pain, abdominal mass, cachexia, or hematuria. Currently, there is no consensus guideline for the treatment of this condition. We report on a 22-year-old man who presented with gross hematuria for 3 weeks. Computed tomography demonstrated a huge right renal mass with a thrombus in the inferior vena cava (IVC) without visceral metastasis. A percutaneous tissue biopsy revealed Ewing’s sarcoma (ES) and the patient received neoadjuvant chemotherapy (doxorubicin and ifosfamide) for four cycles. This reduced the tumor’s size significantly and made it eligible for surgical intervention. Radical nephrectomy and tumor thrombus removal with wedge IVC wall were performed. The final diagnosis of ES was confirmed by the immunohistochemistry of the kidney specimen. After a 5-year follow-up of the patient, clinical and imaging evidence demonstrated that there was no disease recurrence. Wolters Kluwer - Medknow 2023 2023-07-17 /pmc/articles/PMC10471821/ /pubmed/37664090 http://dx.doi.org/10.4103/ua.ua_2_23 Text en Copyright: © 2023 Urology Annals https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Senkhum, Ornsinee Attawettayanon, Worapat Pripatnanont, Choosak Chalieopanyarwong, Virote A primary Ewing’s sarcoma of the kidney: A case report and review of literature |
title | A primary Ewing’s sarcoma of the kidney: A case report and review of literature |
title_full | A primary Ewing’s sarcoma of the kidney: A case report and review of literature |
title_fullStr | A primary Ewing’s sarcoma of the kidney: A case report and review of literature |
title_full_unstemmed | A primary Ewing’s sarcoma of the kidney: A case report and review of literature |
title_short | A primary Ewing’s sarcoma of the kidney: A case report and review of literature |
title_sort | primary ewing’s sarcoma of the kidney: a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471821/ https://www.ncbi.nlm.nih.gov/pubmed/37664090 http://dx.doi.org/10.4103/ua.ua_2_23 |
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