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A primary Ewing’s sarcoma of the kidney: A case report and review of literature

Primary Ewing’s kidney sarcoma is a rare and aggressive cancer with poor treatment outcomes. Furthermore, clinical presentations are nonspecific, such as abdominal pain, abdominal mass, cachexia, or hematuria. Currently, there is no consensus guideline for the treatment of this condition. We report...

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Autores principales: Senkhum, Ornsinee, Attawettayanon, Worapat, Pripatnanont, Choosak, Chalieopanyarwong, Virote
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471821/
https://www.ncbi.nlm.nih.gov/pubmed/37664090
http://dx.doi.org/10.4103/ua.ua_2_23
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author Senkhum, Ornsinee
Attawettayanon, Worapat
Pripatnanont, Choosak
Chalieopanyarwong, Virote
author_facet Senkhum, Ornsinee
Attawettayanon, Worapat
Pripatnanont, Choosak
Chalieopanyarwong, Virote
author_sort Senkhum, Ornsinee
collection PubMed
description Primary Ewing’s kidney sarcoma is a rare and aggressive cancer with poor treatment outcomes. Furthermore, clinical presentations are nonspecific, such as abdominal pain, abdominal mass, cachexia, or hematuria. Currently, there is no consensus guideline for the treatment of this condition. We report on a 22-year-old man who presented with gross hematuria for 3 weeks. Computed tomography demonstrated a huge right renal mass with a thrombus in the inferior vena cava (IVC) without visceral metastasis. A percutaneous tissue biopsy revealed Ewing’s sarcoma (ES) and the patient received neoadjuvant chemotherapy (doxorubicin and ifosfamide) for four cycles. This reduced the tumor’s size significantly and made it eligible for surgical intervention. Radical nephrectomy and tumor thrombus removal with wedge IVC wall were performed. The final diagnosis of ES was confirmed by the immunohistochemistry of the kidney specimen. After a 5-year follow-up of the patient, clinical and imaging evidence demonstrated that there was no disease recurrence.
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spelling pubmed-104718212023-09-02 A primary Ewing’s sarcoma of the kidney: A case report and review of literature Senkhum, Ornsinee Attawettayanon, Worapat Pripatnanont, Choosak Chalieopanyarwong, Virote Urol Ann Case Report Primary Ewing’s kidney sarcoma is a rare and aggressive cancer with poor treatment outcomes. Furthermore, clinical presentations are nonspecific, such as abdominal pain, abdominal mass, cachexia, or hematuria. Currently, there is no consensus guideline for the treatment of this condition. We report on a 22-year-old man who presented with gross hematuria for 3 weeks. Computed tomography demonstrated a huge right renal mass with a thrombus in the inferior vena cava (IVC) without visceral metastasis. A percutaneous tissue biopsy revealed Ewing’s sarcoma (ES) and the patient received neoadjuvant chemotherapy (doxorubicin and ifosfamide) for four cycles. This reduced the tumor’s size significantly and made it eligible for surgical intervention. Radical nephrectomy and tumor thrombus removal with wedge IVC wall were performed. The final diagnosis of ES was confirmed by the immunohistochemistry of the kidney specimen. After a 5-year follow-up of the patient, clinical and imaging evidence demonstrated that there was no disease recurrence. Wolters Kluwer - Medknow 2023 2023-07-17 /pmc/articles/PMC10471821/ /pubmed/37664090 http://dx.doi.org/10.4103/ua.ua_2_23 Text en Copyright: © 2023 Urology Annals https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Senkhum, Ornsinee
Attawettayanon, Worapat
Pripatnanont, Choosak
Chalieopanyarwong, Virote
A primary Ewing’s sarcoma of the kidney: A case report and review of literature
title A primary Ewing’s sarcoma of the kidney: A case report and review of literature
title_full A primary Ewing’s sarcoma of the kidney: A case report and review of literature
title_fullStr A primary Ewing’s sarcoma of the kidney: A case report and review of literature
title_full_unstemmed A primary Ewing’s sarcoma of the kidney: A case report and review of literature
title_short A primary Ewing’s sarcoma of the kidney: A case report and review of literature
title_sort primary ewing’s sarcoma of the kidney: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471821/
https://www.ncbi.nlm.nih.gov/pubmed/37664090
http://dx.doi.org/10.4103/ua.ua_2_23
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