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NKG2A gene variant predicts outcome of immunotherapy in AML and modulates the repertoire and function of NK cells

BACKGROUND: The natural killer (NK) complex (NKC) harbors multiple genes such as KLRC1 (encoding NKG2A) and KLRK1 (encoding NKG2D) that are central to regulation of NK cell function. We aimed at determining to what extent NKC haplotypes impact on NK cell repertoire and function, and whether such gen...

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Detalles Bibliográficos
Autores principales:	Hussein, Brwa Ali, Kristenson, Linnea, Pesce, Silvia, Wöhr, Anne, Tian, Yarong, Hallner, Alexander, Brune, Mats, Hellstrand, Kristoffer, Tang, Ka-Wei, Bernson, Elin, Thorén, Fredrik B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471874/ https://www.ncbi.nlm.nih.gov/pubmed/37648262 http://dx.doi.org/10.1136/jitc-2023-007202

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