Anti-FVIII antibodies in Black and White hemophilia A subjects: do F8 haplotypes play a role?

The most common complication in hemophilia A (HA) treatment, affecting 25% to 30% of patients with severe HA, is the development of alloimmune inhibitors that foreclose the ability of infused factor VIII (FVIII) to participate in coagulation. Inhibitors confer significant pathology on affected indiv...

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Detalles Bibliográficos
Autores principales: Pratt, Kathleen P., Gunasekera, Devi, Vir, Pooja, Tan, Siyuan, Pierce, Glenn F., Olsen, Cara, Butenas, Saulius, Mann, Kenneth G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10471934/
https://www.ncbi.nlm.nih.gov/pubmed/36459498
http://dx.doi.org/10.1182/bloodadvances.2021004909

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