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Upregulated miR‑378a‑3p expression suppresses energy metabolism and promotes apoptosis by targeting a GLUT‑1/ALDOA/PKM2 axis in esophageal carcinoma

Esophageal squamous cell carcinoma (ESCC) is an aggressive malignancy of the digestive system with increasing incidence and mortality rates. The biological roles of microRNA (miR)-378a-3p in tumor cells remain contested, and the mechanisms underlying the functions, energy metabolism, and cell surviv...

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Detalles Bibliográficos
Autores principales: Qu, Yuan, Xue, Shan, Zheng, Yujian, Du, Yajing, Zhang, Guoping, Huang, Liting, Li, Hui, Li, Huiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472027/
https://www.ncbi.nlm.nih.gov/pubmed/37664650
http://dx.doi.org/10.3892/ol.2023.14007