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Host Interactions with Engineered T-cell Micropharmacies

Genetically engineered, cytotoxic, adoptively transferred T cells localize to antigen-positive cancer cells inside patients, but tumor heterogeneity and multiple immune escape mechanisms have prevented the eradication of most solid tumor types. More effective, multifunctional engineered T cells are...

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Detalles Bibliográficos
Autores principales: Bourne, Christopher M., Wallisch, Patrick, Dacek, Megan M., Gardner, Thomas J., Pierre, Stephanie, Vogt, Kristen, Corless, Broderick C., Bah, Mamadou A., Romero-Pichardo, Jesus E., Charles, Angel, Kurtz, Keifer G., Tan, Derek S., Scheinberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472090/
https://www.ncbi.nlm.nih.gov/pubmed/37379366
http://dx.doi.org/10.1158/2326-6066.CIR-22-0879