Absence of Either Ripk3 or Mlkl Reduces Incidence of Hepatocellular Carcinoma Independent of Liver Fibrosis

Nonalcoholic fatty liver disease (NAFLD) is one of the etiologies that contribute to hepatocellular carcinoma (HCC), and chronic inflammation is one of the proposed mediators of HCC. Because necroptosis is a cell death pathway that induces inflammation, we tested whether necroptosis-induced inflamma...

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Detalles Bibliográficos
Autores principales: Mohammed, Sabira, Thadathil, Nidheesh, Ohene-Marfo, Phoebe, Tran, Albert L., Van Der Veldt, Michael, Georgescu, Constantin, Oh, Sangphil, Nicklas, Evan H., Wang, Dawei, Haritha, Nair Hariprasad, Luo, Wenyi, Janknecht, Ralf, Miller, Benjamin F., Wren, Jonathan D., Freeman, Willard M., Deepa, Sathyaseelan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Cell Fate Decisions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472095/
https://www.ncbi.nlm.nih.gov/pubmed/37204757
http://dx.doi.org/10.1158/1541-7786.MCR-22-0820

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