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Development of a Breast Cancer Risk Prediction Model Incorporating Polygenic Risk Scores and Nongenetic Risk Factors for Korean Women

BACKGROUND: To develop a breast cancer prediction model for Korean women using published polygenic risk scores (PRS) combined with nongenetic risk factors (NGRF). METHODS: Thirteen PRS models generated from single or multiple combinations of the Asian and European PRSs were evaluated among 20,434 Ko...

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Detalles Bibliográficos
Autores principales: Choi, Jihye, Ha, Tae-Woong, Choi, Hye-Mi, Lee, Han-Byoel, Shin, Hee-Chul, Chung, Woosung, Han, Wonshik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472098/
https://www.ncbi.nlm.nih.gov/pubmed/37310812
http://dx.doi.org/10.1158/1055-9965.EPI-23-0064