Natural polymers as potential P-glycoprotein inhibitors: Pre-ADMET profile and computational analysis as a proof of concept to fight multidrug resistance in cancer

P-glycoprotein (P-gp) is known as the "multidrug resistance protein" because it contributes to tumor resistance to several different classes of anticancer drugs. The effectiveness of such polymers in treating cancer and delivering drugs has been shown in a wide range of in vitro and in viv...

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Detalles Bibliográficos
Autores principales: Gandla, Kumaraswamy, Islam, Fahadul, Zehravi, Mehrukh, Karunakaran, Anandakumar, Sharma, Indu, Haque, M. Akiful, Kumar, Sanjay, Pratyush, Kumar, Dhawale, Sachin A., Nainu, Firzan, Khan, Sharuk L., Islam, Md Rezaul, Al-Mugren, Kholoud Saad, Siddiqui, Falak A., Emran, Talha Bin, Khandaker, Mayeen Uddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472248/
https://www.ncbi.nlm.nih.gov/pubmed/37662819
http://dx.doi.org/10.1016/j.heliyon.2023.e19454

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