Cargando…

Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo

OBJECTIVES: Providencia is a genus of gram-negative bacteria within the order Enterobacterales, closely related to Proteus and Morganella. While ubiquitous in the environment, some species of Providencia, such as P. rettgeri and P. stuartii, are considered emerging nosocomial pathogens and have been...

Descripción completa

Detalles Bibliográficos
Autores principales: Batinovic, Steven, Chan, Hiu Tat, Stiles, Jason, Petrovski, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472563/
https://www.ncbi.nlm.nih.gov/pubmed/37658299
http://dx.doi.org/10.1186/s12863-023-01153-2
_version_ 1785100103826014208
author Batinovic, Steven
Chan, Hiu Tat
Stiles, Jason
Petrovski, Steve
author_facet Batinovic, Steven
Chan, Hiu Tat
Stiles, Jason
Petrovski, Steve
author_sort Batinovic, Steven
collection PubMed
description OBJECTIVES: Providencia is a genus of gram-negative bacteria within the order Enterobacterales, closely related to Proteus and Morganella. While ubiquitous in the environment, some species of Providencia, such as P. rettgeri and P. stuartii, are considered emerging nosocomial pathogens and have been implicated in urinary tract infection, gastrointestinal illness, and travelers’ diarrhea. Given their intrinsic resistance to many commonly used antibiotics, this study aimed to isolate and sequence bacteriophages targeting a clinical P. rettgeri isolate. DATA DESCRIPTION: Here we report the complete genome sequence of three novel Providencia phages, PibeRecoleta, Stilesk and PatoteraRojo, which were isolated against a clinical P. rettgeri strain sourced from a patient in a metropolitan hospital in Victoria, Australia. The three phages contain dsDNA genomes between 60.7 and 60.9 kb in size and are predicted to encode between 72 and 73 proteins. These three new phages, which share high genomic similarity to two other Providencia phages previously isolated on P. stuartii, serve as important resources in our understanding about Providencia bacteriophages and the potential for future phage-based biotherapies.
format Online
Article
Text
id pubmed-10472563
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-104725632023-09-02 Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo Batinovic, Steven Chan, Hiu Tat Stiles, Jason Petrovski, Steve BMC Genom Data Data Note OBJECTIVES: Providencia is a genus of gram-negative bacteria within the order Enterobacterales, closely related to Proteus and Morganella. While ubiquitous in the environment, some species of Providencia, such as P. rettgeri and P. stuartii, are considered emerging nosocomial pathogens and have been implicated in urinary tract infection, gastrointestinal illness, and travelers’ diarrhea. Given their intrinsic resistance to many commonly used antibiotics, this study aimed to isolate and sequence bacteriophages targeting a clinical P. rettgeri isolate. DATA DESCRIPTION: Here we report the complete genome sequence of three novel Providencia phages, PibeRecoleta, Stilesk and PatoteraRojo, which were isolated against a clinical P. rettgeri strain sourced from a patient in a metropolitan hospital in Victoria, Australia. The three phages contain dsDNA genomes between 60.7 and 60.9 kb in size and are predicted to encode between 72 and 73 proteins. These three new phages, which share high genomic similarity to two other Providencia phages previously isolated on P. stuartii, serve as important resources in our understanding about Providencia bacteriophages and the potential for future phage-based biotherapies. BioMed Central 2023-09-01 /pmc/articles/PMC10472563/ /pubmed/37658299 http://dx.doi.org/10.1186/s12863-023-01153-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Data Note
Batinovic, Steven
Chan, Hiu Tat
Stiles, Jason
Petrovski, Steve
Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
title Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
title_full Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
title_fullStr Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
title_full_unstemmed Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
title_short Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
title_sort complete genome sequences of providencia bacteriophages piberecoleta, stilesk and patoterarojo
topic Data Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472563/
https://www.ncbi.nlm.nih.gov/pubmed/37658299
http://dx.doi.org/10.1186/s12863-023-01153-2
work_keys_str_mv AT batinovicsteven completegenomesequencesofprovidenciabacteriophagespiberecoletastileskandpatoterarojo
AT chanhiutat completegenomesequencesofprovidenciabacteriophagespiberecoletastileskandpatoterarojo
AT stilesjason completegenomesequencesofprovidenciabacteriophagespiberecoletastileskandpatoterarojo
AT petrovskisteve completegenomesequencesofprovidenciabacteriophagespiberecoletastileskandpatoterarojo