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Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo
OBJECTIVES: Providencia is a genus of gram-negative bacteria within the order Enterobacterales, closely related to Proteus and Morganella. While ubiquitous in the environment, some species of Providencia, such as P. rettgeri and P. stuartii, are considered emerging nosocomial pathogens and have been...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472563/ https://www.ncbi.nlm.nih.gov/pubmed/37658299 http://dx.doi.org/10.1186/s12863-023-01153-2 |
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author | Batinovic, Steven Chan, Hiu Tat Stiles, Jason Petrovski, Steve |
author_facet | Batinovic, Steven Chan, Hiu Tat Stiles, Jason Petrovski, Steve |
author_sort | Batinovic, Steven |
collection | PubMed |
description | OBJECTIVES: Providencia is a genus of gram-negative bacteria within the order Enterobacterales, closely related to Proteus and Morganella. While ubiquitous in the environment, some species of Providencia, such as P. rettgeri and P. stuartii, are considered emerging nosocomial pathogens and have been implicated in urinary tract infection, gastrointestinal illness, and travelers’ diarrhea. Given their intrinsic resistance to many commonly used antibiotics, this study aimed to isolate and sequence bacteriophages targeting a clinical P. rettgeri isolate. DATA DESCRIPTION: Here we report the complete genome sequence of three novel Providencia phages, PibeRecoleta, Stilesk and PatoteraRojo, which were isolated against a clinical P. rettgeri strain sourced from a patient in a metropolitan hospital in Victoria, Australia. The three phages contain dsDNA genomes between 60.7 and 60.9 kb in size and are predicted to encode between 72 and 73 proteins. These three new phages, which share high genomic similarity to two other Providencia phages previously isolated on P. stuartii, serve as important resources in our understanding about Providencia bacteriophages and the potential for future phage-based biotherapies. |
format | Online Article Text |
id | pubmed-10472563 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104725632023-09-02 Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo Batinovic, Steven Chan, Hiu Tat Stiles, Jason Petrovski, Steve BMC Genom Data Data Note OBJECTIVES: Providencia is a genus of gram-negative bacteria within the order Enterobacterales, closely related to Proteus and Morganella. While ubiquitous in the environment, some species of Providencia, such as P. rettgeri and P. stuartii, are considered emerging nosocomial pathogens and have been implicated in urinary tract infection, gastrointestinal illness, and travelers’ diarrhea. Given their intrinsic resistance to many commonly used antibiotics, this study aimed to isolate and sequence bacteriophages targeting a clinical P. rettgeri isolate. DATA DESCRIPTION: Here we report the complete genome sequence of three novel Providencia phages, PibeRecoleta, Stilesk and PatoteraRojo, which were isolated against a clinical P. rettgeri strain sourced from a patient in a metropolitan hospital in Victoria, Australia. The three phages contain dsDNA genomes between 60.7 and 60.9 kb in size and are predicted to encode between 72 and 73 proteins. These three new phages, which share high genomic similarity to two other Providencia phages previously isolated on P. stuartii, serve as important resources in our understanding about Providencia bacteriophages and the potential for future phage-based biotherapies. BioMed Central 2023-09-01 /pmc/articles/PMC10472563/ /pubmed/37658299 http://dx.doi.org/10.1186/s12863-023-01153-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Data Note Batinovic, Steven Chan, Hiu Tat Stiles, Jason Petrovski, Steve Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo |
title | Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo |
title_full | Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo |
title_fullStr | Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo |
title_full_unstemmed | Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo |
title_short | Complete genome sequences of Providencia bacteriophages PibeRecoleta, Stilesk and PatoteraRojo |
title_sort | complete genome sequences of providencia bacteriophages piberecoleta, stilesk and patoterarojo |
topic | Data Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472563/ https://www.ncbi.nlm.nih.gov/pubmed/37658299 http://dx.doi.org/10.1186/s12863-023-01153-2 |
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