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Ribosome biogenesis disruption mediated chromatin structure changes revealed by SRAtac, a customizable end to end analysis pipeline for ATAC-seq

The nucleolus is a large nuclear body that serves as the primary site for ribosome biogenesis. Recent studies have suggested that it also plays an important role in organizing chromatin architecture. However, to establish a causal relationship between nucleolar ribosome assembly and chromatin archit...

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Detalles Bibliográficos
Autores principales: Freeman, Trevor F., Zhao, Qiuxia, Surya, Agustian, Rothe, Reed, Cenik, Elif Sarinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472662/
https://www.ncbi.nlm.nih.gov/pubmed/37658321
http://dx.doi.org/10.1186/s12864-023-09576-y