UGCG modulates heart hypertrophy through B4GalT5-mediated mitochondrial oxidative stress and the ERK signaling pathway

Mechanical pressure overload and other stimuli often contribute to heart hypertrophy, a significant factor in the induction of heart failure. The UDP-glucose ceramide glycosyltransferase (UGCG) enzyme plays a crucial role in the metabolism of sphingolipids through the production of glucosylceramide....

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Detalles Bibliográficos
Autores principales: Cui, Shengyu, Zhang, Xutao, Li, Yuhua, Hu, Shan, Wu, Bing, Fang, Zhao, Gao, Jixian, Li, Ming, Wu, Haoliang, Tao, Bo, Xia, Hao, Xu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472674/
https://www.ncbi.nlm.nih.gov/pubmed/37658291
http://dx.doi.org/10.1186/s11658-023-00484-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472674/
https://www.ncbi.nlm.nih.gov/pubmed/37658291
http://dx.doi.org/10.1186/s11658-023-00484-3

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