Computer-Aided Imaging Analysis of Probe-Based Confocal Laser Endomicroscopy With Molecular Labeling and Gene Expression Identifies Markers of Response to Biological Therapy in IBD Patients: The Endo-Omics Study

BACKGROUND: We aimed to predict response to biologics in inflammatory bowel disease (IBD) using computerized image analysis of probe confocal laser endomicroscopy (pCLE) in vivo and assess the binding of fluorescent-labeled biologics ex vivo. Additionally, we investigated genes predictive of anti-tu...

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Detalles Bibliográficos
Autores principales: Iacucci, Marietta, Jeffery, Louisa, Acharjee, Animesh, Grisan, Enrico, Buda, Andrea, Nardone, Olga M, Smith, Samuel C L, Labarile, Nunzia, Zardo, Davide, Ungar, Bella, Hunter, Stuart, Mao, Ren, Cannatelli, Rosanna, Shivaji, Uday N, Parigi, Tommaso Lorenzo, Reynolds, Gary M, Gkoutos, Georgios V, Ghosh, Subrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472745/
https://www.ncbi.nlm.nih.gov/pubmed/36378498
http://dx.doi.org/10.1093/ibd/izac233

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