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System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia

BACKGROUND: To help distinguish vaccine-related adverse events following immunization (AEFI) from coincidental occurrences, active vaccine pharmacovigilance (VP) prospective surveillance programs are needed. From February to May 2021, we assessed the system and facility readiness for implementing ac...

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Autores principales: Zeleke, Eden Dagnachew, Yimer, Getnet, Lisanework, Leuel, Chen, Robert T, Huang, Wan-Ting, Wang, Shu-Hua, Bennett, Sarah D, Makonnen, Eyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472974/
https://www.ncbi.nlm.nih.gov/pubmed/36622733
http://dx.doi.org/10.1093/inthealth/ihac085
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author Zeleke, Eden Dagnachew
Yimer, Getnet
Lisanework, Leuel
Chen, Robert T
Huang, Wan-Ting
Wang, Shu-Hua
Bennett, Sarah D
Makonnen, Eyasu
author_facet Zeleke, Eden Dagnachew
Yimer, Getnet
Lisanework, Leuel
Chen, Robert T
Huang, Wan-Ting
Wang, Shu-Hua
Bennett, Sarah D
Makonnen, Eyasu
author_sort Zeleke, Eden Dagnachew
collection PubMed
description BACKGROUND: To help distinguish vaccine-related adverse events following immunization (AEFI) from coincidental occurrences, active vaccine pharmacovigilance (VP) prospective surveillance programs are needed. From February to May 2021, we assessed the system and facility readiness for implementing active AEFI VP surveillance in Addis Ababa, Ethiopia. METHODS: Selected hospitals were assessed using a readiness assessment tool with scoring measures. The site assessment was conducted via in-person interviews within the specific departments in each hospital. We evaluated the system readiness with a desk review of AEFI guidelines, Expanded Program for Immunization Guidelines and Ethiopian Food and Drug Administration and Ethiopian Public Health Institute websites. RESULTS: Of the hospitals in Addis Ababa, 23.1% met the criteria for our site assessment. During the system readiness assessment, we found that essential components were in place. However, rules, regulations and proclamations pertaining to AEFI surveillance were absent. Based on the tool, the three hospitals (A, B and C) scored 60.6% (94/155), 48.3% (75/155) and 40% (62/155), respectively. CONCLUSIONS: Only one of three hospitals assessed in our evaluation scored >50% for readiness to implement active AEFI surveillance. We also identified the following areas for improvement to ensure successful implementation: training, making guidelines and reporting forms available and ensuring a system that accommodates paper-based and electronic-based recording systems.
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spelling pubmed-104729742023-11-08 System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia Zeleke, Eden Dagnachew Yimer, Getnet Lisanework, Leuel Chen, Robert T Huang, Wan-Ting Wang, Shu-Hua Bennett, Sarah D Makonnen, Eyasu Int Health Original Article BACKGROUND: To help distinguish vaccine-related adverse events following immunization (AEFI) from coincidental occurrences, active vaccine pharmacovigilance (VP) prospective surveillance programs are needed. From February to May 2021, we assessed the system and facility readiness for implementing active AEFI VP surveillance in Addis Ababa, Ethiopia. METHODS: Selected hospitals were assessed using a readiness assessment tool with scoring measures. The site assessment was conducted via in-person interviews within the specific departments in each hospital. We evaluated the system readiness with a desk review of AEFI guidelines, Expanded Program for Immunization Guidelines and Ethiopian Food and Drug Administration and Ethiopian Public Health Institute websites. RESULTS: Of the hospitals in Addis Ababa, 23.1% met the criteria for our site assessment. During the system readiness assessment, we found that essential components were in place. However, rules, regulations and proclamations pertaining to AEFI surveillance were absent. Based on the tool, the three hospitals (A, B and C) scored 60.6% (94/155), 48.3% (75/155) and 40% (62/155), respectively. CONCLUSIONS: Only one of three hospitals assessed in our evaluation scored >50% for readiness to implement active AEFI surveillance. We also identified the following areas for improvement to ensure successful implementation: training, making guidelines and reporting forms available and ensuring a system that accommodates paper-based and electronic-based recording systems. Oxford University Press 2023-01-09 /pmc/articles/PMC10472974/ /pubmed/36622733 http://dx.doi.org/10.1093/inthealth/ihac085 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zeleke, Eden Dagnachew
Yimer, Getnet
Lisanework, Leuel
Chen, Robert T
Huang, Wan-Ting
Wang, Shu-Hua
Bennett, Sarah D
Makonnen, Eyasu
System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia
title System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia
title_full System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia
title_fullStr System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia
title_full_unstemmed System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia
title_short System and facility readiness assessment for conducting active surveillance of adverse events following immunization in Addis Ababa, Ethiopia
title_sort system and facility readiness assessment for conducting active surveillance of adverse events following immunization in addis ababa, ethiopia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10472974/
https://www.ncbi.nlm.nih.gov/pubmed/36622733
http://dx.doi.org/10.1093/inthealth/ihac085
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