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Computer-Aided Drug Design of Novel Derivatives of 2-Amino-7,9-dihydro-8H-purin-8-one as Potent Pan-Janus JAK3 Inhibitors

Rheumatoid arthritis (RA) remains one of the most prevalent autoimmune diseases worldwide. Janus kinase 3 (JAK3) is an essential enzyme for treating autoimmune diseases, including RA. Molecular modeling techniques play a crucial role in the search for new drugs by reducing time delays. In this study...

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Detalles Bibliográficos
Autores principales:	Faris, Abdelmoujoud, Ibrahim, Ibrahim M., Al kamaly, Omkulthom, Saleh, Asmaa, Elhallaoui, Menana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473238/ https://www.ncbi.nlm.nih.gov/pubmed/37570884 http://dx.doi.org/10.3390/molecules28155914

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