A multi-centre, double-blind, randomized, placebo-controlled trial to evaluate the effectiveness and safety of ramelteon for the prevention of postoperative delirium in elderly cancer patients: a study protocol for JORTC-PON2/J-SUPPORT2103/NCCH2103

Postoperative delirium is an important issue in cancer patients, affecting surgical outcomes and the quality of life. Ramelteon is a melatonin receptor agonist with high affinity for MT1 and MT2 receptors. Clinical trials and observational studies in Japan, including in surgical cancer patients, hav...

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Detalles Bibliográficos
Autores principales: Sadahiro, Ryoichi, Hatta, Kotaro, Yamaguchi, Takuhiro, Masanori, Enokido, Matsuda, Yoshinobu, Ogawa, Asao, Iwata, Yusei, Tokoro, Akihiro, Nakahara, Rika, Hirayama, Takatoshi, Yanai, Yuko, Ogawa, Yuko, Kayano, Ayako, Ariyoshi, Keisuke, Oyamada, Shunsuke, Uchitomi, Yosuke, Akechi, Tatsuo, Yamamoto, Noboru, Okita, Natsuko, Yorikane, Eiko, Shimada, Kazuaki, Furukawa, Tetsuya, Hashimoto, Hironobu, Maeda, Makoto, Sato, Tetsufumi, Sekimoto, Asuko, Sasaki, Chiyuki, Saito, Eiko, Uezono, Yasuhito, Matsuoka, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Clinical Trial Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473272/
https://www.ncbi.nlm.nih.gov/pubmed/37340766
http://dx.doi.org/10.1093/jjco/hyad061

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