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Giant condyloma acuminatum surgical management: a case report and literature review

INTRODUCTION AND IMPORTANCE: Condyloma acuminatum (CA) or genital warts, represents a rare sexually transmitted disease caused by the human papillomavirus. Infection occurs when host basal cells are exposed to viral infection through a damaged epithelial barrier, during sexual intercourse, or due to...

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Autores principales: Al-Ghamdi, Ahmed M., Alfalah, Seba, Anwer, Khurshid, Alzaher, Ibrahim, Alsuhaimi, Ahmed A., Aldhafeeri, Sahar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473329/
https://www.ncbi.nlm.nih.gov/pubmed/37663696
http://dx.doi.org/10.1097/MS9.0000000000001102
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author Al-Ghamdi, Ahmed M.
Alfalah, Seba
Anwer, Khurshid
Alzaher, Ibrahim
Alsuhaimi, Ahmed A.
Aldhafeeri, Sahar M.
author_facet Al-Ghamdi, Ahmed M.
Alfalah, Seba
Anwer, Khurshid
Alzaher, Ibrahim
Alsuhaimi, Ahmed A.
Aldhafeeri, Sahar M.
author_sort Al-Ghamdi, Ahmed M.
collection PubMed
description INTRODUCTION AND IMPORTANCE: Condyloma acuminatum (CA) or genital warts, represents a rare sexually transmitted disease caused by the human papillomavirus. Infection occurs when host basal cells are exposed to viral infection through a damaged epithelial barrier, during sexual intercourse, or due to other minor skin abrasions. Giant condyloma acuminatum (GCA) has a higher rate of malignant transformation than CA. CASE PRESENTATION: We are presenting a 44-year-old single gentleman known as a smoker, hepatitis B positive, vitiligo, and hypercholesteromia. He was an alcoholic and had multiple heterosexual relationships abroad. Referred from the dermatology clinic, complaining of genital warts that had increased in size for 10 years. CLINICAL DISCUSSION: CA management includes local applications like imiquimod and podophyllotoxin and clinician-administered treatments such as cryotherapy, surgical excision, electrosurgery, and CO(2) laser therapy. Other options, such as interferon, radiotherapy, or chemotherapy, are available. The selection of therapy should be individualized and based upon consideration of the extent of the disease, patient preference, cost, adverse effects, treatment availability, and the response to previous treatments. Complete surgical excision is the treatment of choice for GCA. CONCLUSION: We present a patient with GCA in the perianal area that was surgically treated with an excellent outcome.
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spelling pubmed-104733292023-09-02 Giant condyloma acuminatum surgical management: a case report and literature review Al-Ghamdi, Ahmed M. Alfalah, Seba Anwer, Khurshid Alzaher, Ibrahim Alsuhaimi, Ahmed A. Aldhafeeri, Sahar M. Ann Med Surg (Lond) Case Reports INTRODUCTION AND IMPORTANCE: Condyloma acuminatum (CA) or genital warts, represents a rare sexually transmitted disease caused by the human papillomavirus. Infection occurs when host basal cells are exposed to viral infection through a damaged epithelial barrier, during sexual intercourse, or due to other minor skin abrasions. Giant condyloma acuminatum (GCA) has a higher rate of malignant transformation than CA. CASE PRESENTATION: We are presenting a 44-year-old single gentleman known as a smoker, hepatitis B positive, vitiligo, and hypercholesteromia. He was an alcoholic and had multiple heterosexual relationships abroad. Referred from the dermatology clinic, complaining of genital warts that had increased in size for 10 years. CLINICAL DISCUSSION: CA management includes local applications like imiquimod and podophyllotoxin and clinician-administered treatments such as cryotherapy, surgical excision, electrosurgery, and CO(2) laser therapy. Other options, such as interferon, radiotherapy, or chemotherapy, are available. The selection of therapy should be individualized and based upon consideration of the extent of the disease, patient preference, cost, adverse effects, treatment availability, and the response to previous treatments. Complete surgical excision is the treatment of choice for GCA. CONCLUSION: We present a patient with GCA in the perianal area that was surgically treated with an excellent outcome. Lippincott Williams & Wilkins 2023-07-31 /pmc/articles/PMC10473329/ /pubmed/37663696 http://dx.doi.org/10.1097/MS9.0000000000001102 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0 (https://creativecommons.org/licenses/by-nd/4.0/) , which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/)
spellingShingle Case Reports
Al-Ghamdi, Ahmed M.
Alfalah, Seba
Anwer, Khurshid
Alzaher, Ibrahim
Alsuhaimi, Ahmed A.
Aldhafeeri, Sahar M.
Giant condyloma acuminatum surgical management: a case report and literature review
title Giant condyloma acuminatum surgical management: a case report and literature review
title_full Giant condyloma acuminatum surgical management: a case report and literature review
title_fullStr Giant condyloma acuminatum surgical management: a case report and literature review
title_full_unstemmed Giant condyloma acuminatum surgical management: a case report and literature review
title_short Giant condyloma acuminatum surgical management: a case report and literature review
title_sort giant condyloma acuminatum surgical management: a case report and literature review
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473329/
https://www.ncbi.nlm.nih.gov/pubmed/37663696
http://dx.doi.org/10.1097/MS9.0000000000001102
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