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The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study

BACKGROUND: We aimed to explore the association between lipids and the survival and walking ability of hip fractures in geriatric patients after surgery. METHODS: Restricted cubic spline (RCS) was established to explore the nonlinear relationship between lipids and 1-year mortality of hip fractures,...

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Autores principales: Zhao, Zhibang, Fan, Wenliang, Wang, Liqiang, Chu, Qingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473408/
https://www.ncbi.nlm.nih.gov/pubmed/37662501
http://dx.doi.org/10.2147/IJGM.S417499
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author Zhao, Zhibang
Fan, Wenliang
Wang, Liqiang
Chu, Qingbo
author_facet Zhao, Zhibang
Fan, Wenliang
Wang, Liqiang
Chu, Qingbo
author_sort Zhao, Zhibang
collection PubMed
description BACKGROUND: We aimed to explore the association between lipids and the survival and walking ability of hip fractures in geriatric patients after surgery. METHODS: Restricted cubic spline (RCS) was established to explore the nonlinear relationship between lipids and 1-year mortality of hip fractures, and the cut-off points were also determined by RCS. Then, the patients were divided into three groups: low, middle, and high levels of LDL-c. Then, the survival and walking ability of patients from different groups were compared, and the Cox regression and Logistics regression were used to identify the relationships between lipids and the survival and walking ability of hip fractures. RESULTS: The patients with middle levels of LDL-c had a significantly high survival probability than those with low or high levels of LDL-c (p < 0.001). The patients with low levels of LDL-c and with high levels of LDL-c may have a poor prognosis compared with patients with middle levels of LDL-c in 6-month mortality, 6-month free walking ability, 1-year mortality, and 1-year free walking ability (All p < 0.05). CONCLUSION: Low and high levels of LDL-c may both relate to the poor survival and walking ability of hip fractures.
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spelling pubmed-104734082023-09-02 The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study Zhao, Zhibang Fan, Wenliang Wang, Liqiang Chu, Qingbo Int J Gen Med Original Research BACKGROUND: We aimed to explore the association between lipids and the survival and walking ability of hip fractures in geriatric patients after surgery. METHODS: Restricted cubic spline (RCS) was established to explore the nonlinear relationship between lipids and 1-year mortality of hip fractures, and the cut-off points were also determined by RCS. Then, the patients were divided into three groups: low, middle, and high levels of LDL-c. Then, the survival and walking ability of patients from different groups were compared, and the Cox regression and Logistics regression were used to identify the relationships between lipids and the survival and walking ability of hip fractures. RESULTS: The patients with middle levels of LDL-c had a significantly high survival probability than those with low or high levels of LDL-c (p < 0.001). The patients with low levels of LDL-c and with high levels of LDL-c may have a poor prognosis compared with patients with middle levels of LDL-c in 6-month mortality, 6-month free walking ability, 1-year mortality, and 1-year free walking ability (All p < 0.05). CONCLUSION: Low and high levels of LDL-c may both relate to the poor survival and walking ability of hip fractures. Dove 2023-08-28 /pmc/articles/PMC10473408/ /pubmed/37662501 http://dx.doi.org/10.2147/IJGM.S417499 Text en © 2023 Zhao et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Zhao, Zhibang
Fan, Wenliang
Wang, Liqiang
Chu, Qingbo
The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study
title The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study
title_full The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study
title_fullStr The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study
title_full_unstemmed The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study
title_short The Paradoxical Association of Lipids with Survival and Walking Ability of Hip Fractures in Geriatric Patients After Surgery: A 1-Year Follow-Up Study
title_sort paradoxical association of lipids with survival and walking ability of hip fractures in geriatric patients after surgery: a 1-year follow-up study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473408/
https://www.ncbi.nlm.nih.gov/pubmed/37662501
http://dx.doi.org/10.2147/IJGM.S417499
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