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IL-21 is required for the maintenance and pathogenesis of murine Vγ4(+) IL-17-producing γδT cells

Murine IL-17-producing γδT (γδT17) cells are divided into two subsets: natural γδT17 (nγδT17) cells, whose development is restricted to the fetal thymus, and inducible γδT17 cells, which require antigen exposure for their IL-17 production and are presumed to develop from Rorc (+) Il17a (-) CCR9 (+)...

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Detalles Bibliográficos
Autores principales: Ishikawa, Junichi, Suto, Akira, Abe, Kazuya, Hayashi, Yuki, Suga, Kensuke, Tanaka, Shigeru, Kageyama, Takahiro, Iwata, Arifumi, Suzuki, Kazumasa, Suzuki, Kotaro, Nakajima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473412/
https://www.ncbi.nlm.nih.gov/pubmed/37662923
http://dx.doi.org/10.3389/fimmu.2023.1211620