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Vibegron shows high selectivity and potent agonist activity for β3-adrenoceptors, irrespective of receptor density
β3-Adrenoceptor (AR) agonists are used to treat patients with an overactive bladder (OAB). Clinical proof-of-concept data have been obtained for the β3-AR agonists vibegron, mirabegron, solabegron, and ritobegron; however, the selectivities of these agents have not been compared directly under the s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473532/ https://www.ncbi.nlm.nih.gov/pubmed/37656760 http://dx.doi.org/10.1371/journal.pone.0290685 |