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Inferring gene regulatory networks using transcriptional profiles as dynamical attractors

Genetic regulatory networks (GRNs) regulate the flow of genetic information from the genome to expressed messenger RNAs (mRNAs) and thus are critical to controlling the phenotypic characteristics of cells. Numerous methods exist for profiling mRNA transcript levels and identifying protein-DNA bindin...

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Detalles Bibliográficos
Autores principales: Li, Ruihao, Rozum, Jordan C., Quail, Morgan M., Qasim, Mohammad N., Sindi, Suzanne S., Nobile, Clarissa J., Albert, Réka, Hernday, Aaron D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473541/
https://www.ncbi.nlm.nih.gov/pubmed/37607190
http://dx.doi.org/10.1371/journal.pcbi.1010991