Multiomics and machine-learning identify novel transcriptional and mutational signatures in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis is a fatal and incurable neurodegenerative disease that mainly affects the neurons of the motor system. Despite the increasing understanding of its genetic components, their biological meanings are still poorly understood. Indeed, it is still not clear to which extent t...

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Detalles Bibliográficos
Autores principales: Catanese, Alberto, Rajkumar, Sandeep, Sommer, Daniel, Masrori, Pegah, Hersmus, Nicole, Van Damme, Philip, Witzel, Simon, Ludolph, Albert, Ho, Ritchie, Boeckers, Tobias M, Mulaw, Medhanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473564/
https://www.ncbi.nlm.nih.gov/pubmed/36883643
http://dx.doi.org/10.1093/brain/awad075

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