Genetically identical twin-pair difference models support the amyloid cascade hypothesis

The amyloid cascade hypothesis has strongly impacted the Alzheimer's disease research agenda and clinical trial designs over the past decades, but precisely how amyloid-β pathology initiates the aggregation of neocortical tau remains unclear. We cannot exclude the possibility of a shared upstre...

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Detalles Bibliográficos
Autores principales: Coomans, Emma M, Tomassen, Jori, Ossenkoppele, Rik, Tijms, Betty M, Lorenzini, Luigi, ten Kate, Mara, Collij, Lyduine E, Heeman, Fiona, Rikken, Roos M, van der Landen, Sophie M, den Hollander, Marijke E, Golla, Sandeep S V, Yaqub, Maqsood, Windhorst, Albert D, Barkhof, Frederik, Scheltens, Philip, de Geus, Eco J C, Visser, Pieter Jelle, van Berckel, Bart N M, den Braber, Anouk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473566/
https://www.ncbi.nlm.nih.gov/pubmed/36892415
http://dx.doi.org/10.1093/brain/awad077

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