CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress

Amyotrophic lateral sclerosis is a progressive neurodegenerative disease that affects motor neurons in the spinal cord, brainstem and motor cortex, leading to paralysis and eventually to death within 3–5 years of symptom onset. To date, no cure or effective therapy is available. The role of chronic...

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Detalles Bibliográficos
Autores principales: De Lorenzo, Francesca, Lüningschrör, Patrick, Nam, Jinhan, Beckett, Liam, Pilotto, Federica, Galli, Emilia, Lindholm, Päivi, Rüdt von Collenberg, Cora, Mungwa, Simon Tii, Jablonka, Sibylle, Kauder, Julia, Thau-Habermann, Nadine, Petri, Susanne, Lindholm, Dan, Saxena, Smita, Sendtner, Michael, Saarma, Mart, Voutilainen, Merja H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473573/
https://www.ncbi.nlm.nih.gov/pubmed/36928391
http://dx.doi.org/10.1093/brain/awad087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473573/
https://www.ncbi.nlm.nih.gov/pubmed/36928391
http://dx.doi.org/10.1093/brain/awad087

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