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A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ
Unbiased chemical biology strategies for direct readout of protein interactome remodelling by small molecules provide advantages over target-focused approaches, including the ability to detect previously unknown targets, and the inclusion of chemical off-compete controls leading to high-confidence i...
Autores principales: | Tao, Andrew J., Jiang, Jiewei, Gadbois, Gillian E., Goyal, Pavitra, Boyle, Bridget T., Mumby, Elizabeth J., Myers, Samuel A, English, Justin G., Ferguson, Fleur M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473607/ https://www.ncbi.nlm.nih.gov/pubmed/37662262 http://dx.doi.org/10.1101/2023.08.21.554211 |
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