A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes in situ

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Unbiased chemical biology strategies for direct readout of protein interactome remodelling by small molecules provide advantages over target-focused approaches, including the ability to detect previously unknown targets, and the inclusion of chemical off-compete controls leading to high-confidence i...

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Detalles Bibliográficos
Autores principales: Tao, Andrew J., Jiang, Jiewei, Gadbois, Gillian E., Goyal, Pavitra, Boyle, Bridget T., Mumby, Elizabeth J., Myers, Samuel A, English, Justin G., Ferguson, Fleur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473607/
https://www.ncbi.nlm.nih.gov/pubmed/37662262
http://dx.doi.org/10.1101/2023.08.21.554211
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