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Reprogramming of breast tumor-associated macrophages with modulation of arginine metabolism

HER2+ breast tumors have abundant immune-suppressive cells, including M2-type tumor associated macrophages (TAMs). While TAMs consist of the immune-stimulatory M1-type and immune-suppressive M2-type, M1/M2-TAM ratio is reduced in immune-suppressive tumors, contributing to their immunotherapy refract...

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Detalles Bibliográficos
Autores principales:	Fernando, Veani, Zheng, Xunzhen, Sharma, Vandana, Furuta, Saori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473631/ https://www.ncbi.nlm.nih.gov/pubmed/37662241 http://dx.doi.org/10.1101/2023.08.22.554238

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