Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons

Antigen processing is critical for producing epitope peptides that are presented by HLA molecules for T cell recognition. Therapeutic vaccines aim to harness these epitopes for priming cytotoxic T cell responses against cancer and pathogens, but insufficient processing often reduces vaccine efficacy...

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Detalles Bibliográficos
Autores principales: Truex, Nicholas L., Mohapatra, Somesh, Melo, Mariane, Rodriguez, Jacob, Li, Na, Abraham, Wuhbet, Sementa, Deborah, Touti, Faycal, Keskin, Derin B., Wu, Catherine J., Irvine, Darrell J., Gómez-Bombarelli, Rafael, Pentelute, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473641/
https://www.ncbi.nlm.nih.gov/pubmed/37662211
http://dx.doi.org/10.1101/2023.08.22.554289

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