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Rise in frequency of lasR mutant Pseudomonas aeruginosa among keratitis isolates between 1993 and 2021

Pseudomonas aeruginosa causes severe vision threatening keratitis. LasR is a transcription factor that regulates virulence associated genes in response to the quorum sensing molecule N-3-oxo-dodecanoyl-L-homoserine lactone. P. aeruginosa isolates with lasR mutations are characterized by an iridescen...

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Detalles Bibliográficos
Autores principales:	Shanks, Robert M. Q., Atta, Sarah, Stella, Nicholas A., Sundar-Raj, Chollapadi V., Romanowski, John E., Grewel, Arman S., Shanks, Hazel Q., Mumper, Sonya M., Dhaliwal, Deepinder K., Mammen, Alex, Callaghan, Jake D., Calvario, Rachel C., Romanowski, Eric G., Kowalski, Regis P., Zegans, Michael E., Jhanji, Vishal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473646/ https://www.ncbi.nlm.nih.gov/pubmed/37662319 http://dx.doi.org/10.1101/2023.08.22.554354

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