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MASH: MEDIATION ANALYSIS OF SURVIVAL OUTCOME AND HIGH-DIMENSIONAL OMICS MEDIATORS WITH APPLICATION TO COMPLEX DISEASES

Environmental exposures such as cigarette smoking influence health outcomes through intermediate molecular phenotypes, such as the methylome, transcriptome, and metabolome. Mediation analysis is a useful tool for investigating the role of potentially high-dimensional intermediate phenotypes in the r...

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Detalles Bibliográficos
Autores principales: CHI, BY SUNYI, FLOWERS, CHRISTOPHER R, LI, ZIYI, HUANG, XUELIN, WEI, PENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473652/
https://www.ncbi.nlm.nih.gov/pubmed/37662296
http://dx.doi.org/10.1101/2023.08.22.554286