Microglia mediate contact-independent neuronal pruning via secreted Neuraminidase-3 associated with extracellular vesicles

Neurons communicate with each other through electrochemical transmission at synapses. Microglia, the resident immune cells of the central nervous system, can prune these synapses through a variety of contact-dependent and -independent means. Microglial secretion of active sialidase enzymes upon expo...

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Detalles Bibliográficos
Autores principales: Delaveris, Corleone S., Wang, Catherine L., Riley, Nicholas M., Li, Sherry, Kulkarni, Rishikesh U., Bertozzi, Carolyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473657/
https://www.ncbi.nlm.nih.gov/pubmed/37662421
http://dx.doi.org/10.1101/2023.08.21.554214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473657/
https://www.ncbi.nlm.nih.gov/pubmed/37662421
http://dx.doi.org/10.1101/2023.08.21.554214

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