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D-β-hydroxybutyrate stabilizes the hippocampal CA3-CA1 circuit during acute insulin resistance
1. The brain primarily relies on glycolysis for mitochondrial respiration but switches to alternative fuels such as ketone bodies (KB) during low glucose availability. Neuronal KB uptake, which does not rely on the glucose transporter 4 (GLUT4) and insulin, has shown promising clinical applications...
Autores principales: | Kula, Bartosz, Antal, Botond, Weistuch, Corey, Gackière, Florian, Barre, Alexander, Velado, Victor, Hubbard, Jeffrey M, Kukley, Maria, Mujica-Parodi, Lilianne R, Smith, Nathan A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473684/ https://www.ncbi.nlm.nih.gov/pubmed/37662316 http://dx.doi.org/10.1101/2023.08.23.554428 |
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