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Osterix-driven LINC complex disruption in vivo diminishes bone microarchitecture in 8-week male mice but not after 6-week voluntary wheel running

The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex is a crucial connective component between the nuclear envelope and the cytoskeleton involving various cellular processes including nuclear positioning, nuclear architecture, and mechanotransduction. How LINC complexes regulate bone formati...

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Detalles Bibliográficos
Autores principales: Birks, Scott, Howard, Sean, O’Rourke, Caroline, Thompson, William R, Lau, Anthony, Uzer, Gunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473717/
https://www.ncbi.nlm.nih.gov/pubmed/37662368
http://dx.doi.org/10.1101/2023.08.24.554623