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How Many Patients Do You Need? Investigating Trial Designs for Anti-Seizure Treatment in Acute Brain Injury Patients

OBJECTIVES: Epileptiform activity (EA) worsens outcomes in patients with acute brain injuries (e.g., aneurysmal subarachnoid hemorrhage [aSAH]). Randomized trials (RCTs) assessing anti-seizure interventions are needed. Due to scant drug efficacy data and ethical reservations with placebo utilization...

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Detalles Bibliográficos
Autores principales:	Parikh, Harsh, Sun, Haoqi, Amerineni, Rajesh, Rosenthal, Eric S., Volfovsky, Alexander, Rudin, Cynthia, Westover, M. Brandon, Zafar, Sahar F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473786/ https://www.ncbi.nlm.nih.gov/pubmed/37662339 http://dx.doi.org/10.1101/2023.08.21.23294339

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