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Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm

In some patients with myeloproliferative neoplasms (MPN), two genetic mutations are often found, JAK2 V617F and one in the TET2 gene. Whether or not one mutation is present will influence how the other subsequent mutation affects the regulation of gene expression. When both mutations are present, th...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Shtylla, Blerta, Chou, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473807/
https://www.ncbi.nlm.nih.gov/pubmed/37662184
http://dx.doi.org/10.1101/2023.08.16.23294177

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