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Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm
In some patients with myeloproliferative neoplasms (MPN), two genetic mutations are often found, JAK2 V617F and one in the TET2 gene. Whether or not one mutation is present will influence how the other subsequent mutation affects the regulation of gene expression. When both mutations are present, th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473807/ https://www.ncbi.nlm.nih.gov/pubmed/37662184 http://dx.doi.org/10.1101/2023.08.16.23294177 |
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