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Dynamic allosteric networks drive adenosine A(1) receptor activation and G-protein coupling
G-protein coupled receptors (GPCRs) present specific activation pathways and signaling among receptor subtypes. Hence, an extensive knowledge of the structural dynamics of the receptor is critical for the development of therapeutics. Here, we target the adenosine A(1) receptor (A(1)R), for which a n...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10473838/ https://www.ncbi.nlm.nih.gov/pubmed/37656635 http://dx.doi.org/10.7554/eLife.90773 |